Glutamate, Microdialysis, and Cerebral Ischemia
نویسندگان
چکیده
منابع مشابه
Glutamate excitotoxicity in transient global cerebral ischemia.
The glutamate excitotoxicity hypothesis of ischemic cell damage holds that cell damage caused by transient cerebral ischemia is triggered by glutamate, released during ischemia from the intracellular compartment into the synaptic cleft: high extracellular glutamate levels activate ionotropic glutamate receptors, thus inducing an overflow of calcium ions into the neurones and a calcium-induced a...
متن کاملHippocampal Glutamate Concentrations After Repeated Cerebral Ischemia in Rabbits
29. Nakata N, Kato H, Liu Y, Kogure K. Effects of pretreatment with sublethal ischemia onthe extracellular glutamate concentrations during secondary ischemia in the gerbil hippocampus evaluated with intracerebral microdialysis. Neurosci Lett.1992;138:86-88.
متن کاملMicrodialysis in Liver Ischemia and Reperfusion injury
.................................................................................................................................. 9 ABBREVIATIONS ....................................................................................................................... 11 DEFINITIONS ......................................................................................................................
متن کاملCerebral ischemia in aneurysmal subarachnoid hemorrhage: a correlative microdialysis-PET study.
BACKGROUND AND PURPOSE Cerebral microdialysis (MD) is discussed as a technique for detection of cerebral ischemia in subarachnoid hemorrhage; however, clinical data on cerebral blood flow (CBF) are limited in these patients. The main objective of this study was to investigate whether pathological MD parameters reflect a reduced regional CBF (rCBF) determined by 15O-H2O PET. METHODS Thirteen s...
متن کامل[Cerebral microdialysis in the current clinical setting].
Cerebral microdialysis, introduced in experimental studies 40 years ago, has been used clinically since 1992 for the neurochemical monitoring of patients in intensive care. The principles underlying this technique are closely related to brain metabolism. The study of the metabolites detected at brain interstitial tissue level, through the semipermeable membrane of the device, allows us to asses...
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ژورنال
عنوان ژورنال: Anesthesiology
سال: 2009
ISSN: 0003-3022
DOI: 10.1097/aln.0b013e318194b620